{"id":1896,"date":"2018-12-11T14:23:52","date_gmt":"2018-12-11T13:23:52","guid":{"rendered":"https:\/\/www.platelets.eu\/publikationen\/"},"modified":"2023-12-06T16:06:18","modified_gmt":"2023-12-06T15:06:18","slug":"publikationen","status":"publish","type":"page","link":"https:\/\/www.platelets.eu\/de\/tr240\/publikationen\/","title":{"rendered":"Publikationen"},"content":{"rendered":"\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t

2023<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t\t\t

Beck S, \u00d6ftering P, Li R, Hemmen K, Nagy M, Wang Y, Zarpellon A, Schuhmann MK, Stoll G, Ruggeri ZM, Heinze KG, Heemskerk JWM, Ruf W*, Stegner D*, Nieswandt B*. Platelet glycoprotein V spatio-temporally controls fibrin formation<\/strong>. Nat Cardiovasc Res. 2023. doi: 10.1038\/s44161-023-00254-6. PMID: 37206993.<\/a><\/p>

Bellut M, Bieber M, Kraft P, Weber ANR, Stoll G, Schuhmann MK. Delayed NLRP3 inflammasome inhibition ameliorates subacute stroke progression in mice<\/strong>. J Neuroinflammation. 2023. doi: 10.1186\/s12974-022-02674-w. PMID: 36600259.<\/a><\/p>

Feick J, Pham M, M\u00e4rz AG, Vogt ML, Strinitz M, Stoll G, Schuhmann MK, Kollikowski AM. Distinct Alterations in Oxygenation, Ion Composition and Acid-Base Balance in Cerebral Collaterals During Large-Vessel Occlusion Stroke<\/strong>. Clin Neuroradiol. 2023. doi: 10.1007\/s00062-023-01296-w. PMID: 37284875.<\/a><\/p>

Feil S, Stowbur D, Schorg BF, Ehrlichmann W, Reischl G, Kneilling M, Pichler BJ, Feil R. 2023.\u00a0Noninvasive detection of smooth muscle cell-derived hot spots to study atherosclerosis by PET\/MRI in mice.<\/strong>\u00a0Circ Res\u00a0<\/em>132, 747.\u00a0<\/i><\/strong>doi:10.1161\/CIRCRESAHA.122.322296.<\/span><\/a><\/p>

Fink A, Rohlfing AK, Dicenta V, Schaale D, Kremser M, Laspa Z, Sigle M, Fu X, Pelzer A, Fischer M, M\u00fcnzer P, Castor T, M\u00fcller KAL, Borst O, L\u00e4mmerhofer M, Gawaz MP. The Subtilisin-Like Protease Furin Regulates Hemin-Dependent Ectodomain Shedding of Glycoprotein VI<\/strong>. Thromb Haemost. 2023. doi: 10.1055\/s-0043-1768057. PMID: 37037200.<\/a><\/p>

Gawaz M, Geisler T, Borst O. Current concepts and novel targets for antiplatelet therapy<\/strong>. Nat Rev Cardiol. 2023. doi: 10.1038\/s41569-023-00854-6. PMID: 37016032.<\/a><\/p>

Goldschmied A, Drotleff B, Winter S, Schaeffeler E, Schwab M, Gawaz M, Geisler T, Rath D. Platelet miRNAs: differential expression in coronary artery disease and associations with course of left ventricular systolic function<\/strong>. BMC Cardiovasc Disord. 2023. doi: 10.1186\/s12872-023-03362-0. PMID: 37438691.<\/a><\/p>

Haarmann A, Vollmuth C, Kollikowski AM, Heuschmann PU, Pham M, Stoll G, Neugebauer H, Schuhmann MK. Vasoactive Soluble Endoglin: A Novel Biomarker Indicative of Reperfusion after Cerebral Large-Vessel Occlusion<\/strong>. Cells. 2023. doi: 10.3390\/cells12020288. PMID: 36672223.<\/a><\/p>

Harm T, Dittrich K, Brun A, Fu X, Frey M, Petersen Uribe A, Schwarz FJ, Rohlfing AK, Castor T, Geisler T, Rath D, L\u00e4mmerhofer M, Gawaz MP. Large-scale lipidomics profiling reveals characteristic lipid signatures associated with an increased cardiovascular risk<\/strong>. Clin Res Cardiol. 2023. doi: 10.1007\/s00392-023-02260-x. PMID: 37470807.<\/a><\/p>

Kazenwadel J, Berezhnoy G, Cannet C, Sch\u00e4fer H, Geisler T, Rohlfing AK, Gawaz M, Merle U, Trautwein C. Stratification of hypertension and SARS-CoV-2 infection by quantitative NMR spectroscopy of human blood serum<\/strong>. Commun Med (Lond). 2023. doi: 10.1038\/s43856-023-00365-y. PMID: 37845506.<\/a><\/p>

Konrad K, Gao S. Zurbriggen M, Nagel G. Optogenetic Methods in Plant Biology<\/strong>. Annu Rev Plant Biol. 2023. doi: 10.1146\/annurev-arplant-071122-094840. PMID: 37216203.<\/a><\/p>

Langnau C, Janing H, Kocaman H, Gekeler S, G\u00fcnter M, Petersen-Uribe \u00c1, Jaeger P, Koch B, Kreisselmeier KP, Castor T, Rath D, Gawaz MP, Autenrieth SE, Mueller KAL. Recovery of systemic hyperinflammation in patients with severe SARS-CoV-2 infection<\/strong>. Biomarkers. 2023. doi: 10.1080\/1354750X.2022.2148745. PMID: 36377411.<\/a><\/p>

Lin, F., Tang, R., Zhang, C, Scholz N, Nagel G, Gao S. Combining different ion-selective channelrhodopsins to control water flux by light<\/strong>. Pflugers Arch – Eur J Physiol. 2023. doi: 10.1007\/s00424-023-02853-5. PMID: 37670155.<\/a><\/p>

Oehmcke-Hecht S, Maletzki C, Surabhi S, Siemens S, Khaimov V, John LM, Peter SM, Hammerschmidt S, and Kreikemeyer B. Procoagulant activity of blood and microvesicles Is disturbed by pneumococcal pneumolysin, which interacts with coagulation factors<\/strong>. J Innate Immun. 2023. doi: 10.1159\/000525479. PMID: 35843205.<\/a><\/p>

Palma-Barqueros V*, Bastida J, L\u00f3pez Andreo M, Zamora-C\u00e1novas A, Zaninetti C, Ruiz-Pividal J, Bohdan N, Padilla J, Teruel-Montoya R, Mar\u00edn-Quilez A, Revilla N, S\u00e1nchez-Fuentes A, Rodriguez-Alen A, Benito R, Vicente V, Iturbe T, Greinacher A, Lozano M, Rivera J. Platelet transcriptome analysis in patients with germline RUNX1 mutations<\/strong>. J Thromb Haemost. 2023. doi: 10.1016\/j.jtha.2023.01.023. PMID: 36736831.<\/a><\/p>

Rizzo G, Gropper J, Piollet M, Vafadarnejad E, Rizakou A, Bandi SR, Arampatzi P, Krammer T, DiFabion N, Dietrich O, Arias-Loza AP, Prinz M, Mack M, Schlepckow K, Haass C, Silvestre JS, Zernecke A, Saliba AE, Cochain C. Dynamics of monocyte-derived macrophage diversity in experimental myocardial infarction<\/strong>. Cardiovasc Res. 2023. doi: 10.1093\/cvr\/cvac113. PMID: 35950218.<\/a><\/p>

Sch\u00f6nborn L*, Seck S, Thiele T, Kaderali L, Hoffmann T, Hlinka A, Lindhoff-Last E, V\u00f6lker U, Selleng K, Buoninfante A, Cavaleri M, Greinacher A. Long-term outcome in Vaccine-induced Immune Thrombocytopenia and Thrombosis<\/strong>. J Thromb Haemost. 2023. doi: 10.1016\/j.jtha.2023.06.027. PMID: 37394120.<\/a><\/p>

Schories C, Martus P, Guan T, Henes JK, Witte A, M\u00fcller K, Geisler T, Chatterjee M, Gawaz M, Rath D. Platelet versus plasma CXCL14, coronary artery disease, and clinical outcomes<\/strong>. Res Pract Thromb Haemost. 2023. doi: 10.1016\/j.rpth.2023.100165. PMID: 37255851.<\/a><\/p>

Spindler M, Mott K, Schulze H, Bender M. Rapid isolation of mature murine primary megakaryocytes by size exclusion via filtration<\/strong>. Platelets. 2023. doi: 10.1080\/09537104.2023.2192289. PMID: 36992536.<\/a><\/p>

Stehle D, Barresi M, Schulz J, Feil R. 2023.\u00a0Heterogeneity of cGMP signalling in tumour cells and the tumour microenvironment: Challenges and chances for cancer pharmacology and therapeutics.<\/strong>\u00a0<\/span>Pharmacol Ther<\/em>\u00a0242, 108337. doi: 10.1016\/j.pharmthera.2023.108337. PMID: 36623589.<\/a><\/p>

Strauss J, Deng L, Gao S, Toseland A, Bachy C, Zhang C, Kirkham A, Hopes A, Utting R, Joest EF, Tagliabue A, L\u00f6w C, Worden AZ, Nagel G, Mock T. Plastid-localized xanthorhodopsin increases diatom biomass and ecosystem productivity in iron-limited surface oceans<\/strong>. Nat Microbiol. 2023. doi: 10.1038\/s41564-023-01498-5. PMID: 37845316.<\/a><\/p>

Zaninetti C*, Lein\u00f8e E, Lozano M, Rossing M, Bastida J, Zetterberg E, Rivera J, Greinacher A. Validation of immunofluorescence analysis of blood smears in patients with inherited platelet disorders<\/strong>. J Thromb Haemost. 2023. doi: 10.1016\/j.jtha.2022.12.031. PMID: 36732160.<\/a><\/p>

Zernecke A, Erhard F, Weinberger T, Schulz C, Ley K, Saliba AE, Cochain C. Integrated single-cell analysis-based classification of vascular mononuclear phagocytes in mouse and human atherosclerosis<\/strong>. Cardiovasc Res. 2023. doi: 10.1093\/cvr\/cvac161. PMID: 36190844.<\/a><\/p>

Zhao X, Alibhai D, Walsh TG, Tarassova N, Englert M, Birol SZ, Li Y, Williams CM, Neal CR, Burkard P, Cross SJ, Aitken EW, Waller AK, Beltr\u00e1n JB, Gunning PW, Hardeman EC, Agbani EO, Nieswandt B, Hers I, Ghevaert C, Poole AW. Highly efficient platelet generation in lung vasculature reproduced by microfluidics<\/strong>. Nat Commun. 2023. doi: 10.1038\/s41467-023-39598-9. PMID: 37419900.<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

\n\t\t\t\t
\n\t\t\t\t\t

2022<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t\t\t

Alban S*, Neupane S, Girreser U, S\u00f6nnichsen F, Greinacher A.<\/span>The COVID-19 vaccine ChAdOx1-S is not contaminated with sulfated glycosaminoglycans<\/b>. <\/span>J Thromb Haemost. 2022. <\/span>
<\/span>doi: 10.1111\/jth.15633 PMID: 34971474.<\/span><\/a><\/p>

Aurich K*, Wesche J, Ulbricht M, Otto O, Greinacher A, Palankar R. Divalent magnesium restores cytoskeletal storage lesions in cold-stored platelet concentrates<\/strong>. Sci Rep. 2022. doi: 10.1038\/s41598-022-10231-x. PMID: 35422472.<\/a><\/p>

Baumann J, Sachs L, Otto O, Schoen I, Nestler P, Zaninetti C, Kenny M, Kranz R, von Eysmondt H, Rodriguez J, Sch\u00e4ffer TE, Nagy Z, Greinacher A, Palankar R, Bender M. Reduced platelet forces underlie impaired hemostasis in mouse models of MYH9-related disease<\/strong>. Sci Rep. 2022. doi: 10.1038\/s41598-022-26821-8. PMID: 35584211.<\/a><\/p>

Baumann J, Spindler M, Throm Y, L\u00fcbbert M, Bender M. Absence of early platelet increment in healthy mice during decitabine treatment<\/strong>. Sci Adv. 2022. doi: 10.1126\/sciadv.abn2627. PMID: 36564544.<\/a><\/p>

Bayrak A, Mohr F, Kolb K, Szpakowska M, Shevchenko E, Dicenta V, Rohlfing AK, Kudolo M, Pantsar T, G\u00fcnther M, Kaczor AA, Poso A, Chevign\u00e9 A, Pillaiyar T, Gawaz M, Laufer SA. Discovery and Development of First-in-Class ACKR3\/CXCR7 Superagonists for Platelet Degranulation Modulation<\/strong>. J Med Chem. 2022. doi: 10.1021\/acs.jmedchem.2c01198. PMID: 36150079.<\/a><\/p>

Becker IC, Nagy Z, Manukjan G, Haffner-Luntzer M, Englert M, Heib T, V\u00f6gtle T, Gross C, Bharti R, Dietrich S, Mott K, Heck J, Stegmaier S, Baranowsky A, Schinke T, Schlegel N, Heckel T, Stegner D, Pleines I, Ignatius A, Schulze H, Nieswandt B. <\/span>G6b-B regulates an essential step in megakaryocyte maturation<\/b>. <\/span>Blood Adv. 2022 Feb 8: bloodadvances.2021006151. <\/span>
<\/span>doi: 10.1182\/bloodadvances.2021006151. Online ahead of print. PMID: 35134123.<\/span><\/a><\/p>

Bellut M, Raimondi AT, Haarmann A, Zimmermann L, Stoll G, Schuhmann MK. NLRP3 Inhibition Reduces rt-PA Induced Endothelial Dysfunction under Ischemic Conditions<\/strong>. Biomedicines. 2022. doi: 10.3390\/biomedicines10040762. PMID: 35453512.<\/a><\/p>

Bieber M, Schuhmann MK, Bellut M, Stegner D, Heinze KG, Pham M, Nieswandt B, Stoll G. Blockade of Platelet Glycoprotein Ib\u03b1 Augments Neuroprotection in Orai2-Deficient Mice during Middle Cerebral Artery Occlusion<\/strong>. Int J Mol Sci. 2022. doi: 10.3390\/ijms23169496. PMID: 36012752.<\/a><\/p>

Brandhofer M, Hoffmann A, Blanchet X, Siminkovitch E, Rohlfing AK, El Bounkari O, Nestele JA, Bild A, Kontos C, Hille K, Rohde V, Fr\u00f6hlich A, Golemi J, Gokce O, Krammer C, Scheiermann P, Tsilimparis N, Sachs N, Kempf WE, Maegdefessel L, Otabil MK, Megens RTA, Ippel H, Koenen RR, Luo J, Engelmann B, Mayo KH, Gawaz M, Kapurniotu A, Weber C, von Hundelshausen P, Bernhagen J. Heterocomplexes between the atypical chemokine MIF and the CXC-motif chemokine CXCL4L1 regulate inflammation and thrombus formation<\/strong>. Cell Mol Life Sci. 2022. doi: 10.1007\/s00018-022-04539-0. PMID: 36094626.<\/a><\/p>

Breitenbach T, Englert N, Osmanoglu \u00d6, Rukoyatkina N, Wangorsch G, Heinze K, Friebe A, Butt E, Feil R, Dittrich M, Gambaryan S, Dandekar T. 2022.\u00a0A modular systems biological modelling framework studies cyclic nucleotide signaling in platelets.<\/strong>\u00a0<\/span>J Theor Biol<\/em>\u00a0550, 111222. doi: 10.1016\/j.jtbi.2022.111222. PMID: 35843440.<\/a><\/p>

Chatterjee M. Atypical Roles of the Chemokine Receptor ACKR3\/CXCR7 in Platelet Pathophysiology<\/strong>. Cells. 2022. doi: 10.3390\/cells11020213. PMID: 35053329.<\/a><\/p>

Chen F, Duan X, Yu Y, Yang S, Chen Y, Gee CE, Nagel G, Zhang K, Gao S, Shen Y. Visual function restoration with a highly sensitive and fast Channelrhodopsin in blind mice<\/strong>. Signal Transduct Target Ther. 2022. doi: 10.1038\/s41392-022-00935-x. PMID: 35430811.<\/a><\/p>

Englert M, Aurbach K, Becker IC, Gerber A, Heib T, Wackerbarth LM, Kusch C, Mott K, Araujo GHM, Baig AA, D\u00fctting S, Knaus UG, Stigloher C, Schulze H, Nieswandt B, Pleines I, Nagy Z. Impaired microtubule dynamics contribute to microthrombocytopenia in RhoB-deficient mice<\/strong>. Blood Adv. 2022. doi: 10.1182\/bloodadvances.2021006545. PMID: 35819450.<\/a><\/p>

Feil R, Lehners M, Stehle D, Feil S. Visualising and understanding cGMP signals in the cardiovascular system<\/strong>. Br J Pharmacol. 2022. doi: 10.1111\/bph.15500. PMID: 33880767.<\/a><\/p>

Fregin B, Biedenweg D, Otto O. Interpretation of cell mechanical experiments in microfluidic systems depend on the choice of cellular shape descriptors<\/strong>. Biomicrofluidics. 2022. doi: 10.1063\/5.0084673. PMID: 35541026.<\/a><\/p>

Geisler T, Branch K, Nikol S. Clinical experience with dual pathway inhibition therapy: case series and mini review<\/strong>. Eur Heart J Case Rep. 2022. doi: 10.1093\/ehjcr\/ytac201. PMID: 35854882.<\/a><\/p>

Geisler T, Poli S, Huber K, Rath D, Aidery P, Kristensen SD, Storey RF, Ball A, Collet JP, Berg JT. Resumption of Antiplatelet Therapy after Major Bleeding<\/strong>. Thromb Haemost. 2022. doi: 10.1055\/s-0042-1750419. PMID: 35785817.<\/a><\/p>

Giles J*, Steiner H, Rollin J, Shaffer C, Momozawa Y, Mushiroda T, Inai C, Selleng K, Thiele T, Pouplard C, Heddle N, Kubo M, Miller E, Martinez K, Phillips E, Warkentin T, Gruel Y, Greinacher A, Roden D, Karnes J. Genome-wide association study of platelet factor 4\/heparin antibodies in heparin-induced thrombocytopenia<\/strong>. Blood Adv. 2022. doi: 10.1182\/bloodadvances.2022007673. PMID: 35533259.<\/a><\/p>

Greinacher A, Langer F, Schonborn L, Thiele T, Haddad M, Renne T, Rollin J, Gruel Y, Warkentin TE. Platelet-activating anti-PF4 antibodies mimicking VITT antibodies in an unvaccinated patient with monoclonal gammopathy<\/strong>. Haematologica. 2022. doi: 10.3324\/haematol.2021.280366. PMID: 34965704.<\/a><\/p>

Guan T, Emschermann F, Schories C, Groga-Bada P, Martus P, Borst O, Gawaz M, Geisler T, Rath D, Chatterjee M. Platelet SR-PSOX\/CXCL16-CXCR6 Axis Influences Thrombotic Propensity and Prognosis in Coronary Artery Disease<\/strong>. Int J Mol Sci. 2022. doi: 10.3390\/ijms231911066. PMID: 36232370.<\/a><\/p>

Haarmann A, Zimmermann L, Bieber M, Silwedel C, Stoll G, Schuhmann MK. Regulation and Release of Vasoactive Endoglin by Brain Endothelium in Response to Hypoxia\/Reoxygenation in Stroke<\/strong>. Int J Mol Sci. 2022. doi: 10.3390\/ijms23137085. PMID: 35806090.<\/a><\/p>

Hearn JI, Green TN, Hisey CL, Bender M, Josefsson EC, Knowlton N, Baumann J, Poulsen RC, Bohlander SK, Kalev-Zylinska ML. Deletion of Grin1 in mouse megakaryocytes reveals NMDA receptor role in platelet function and proplatelet formation<\/strong>. Blood. 2022. doi: 10.1182\/blood.2021014000. PMID: 35245376.<\/a><\/p>

Heil HS, Aigner M, Maier S, Gupta P, Evers LMC, G\u00f6b V, Kusch C, Meub M, Nieswandt B, Stegner D, Heinze KG. <\/span>Mapping densely packed \u03b1IIb\u03b23 receptors in murine blood platelets with expansion microscopy<\/b>. <\/span>Platelets. 2022 Feb 2:1-10. <\/span>
<\/span>doi: 10.1080\/09537104.2021.2023735. Online ahead of print. PMID: 35109754.<\/span><\/a><\/p>

Jahn K, Handtke S, Palankar R, Kohler TP, Wesche J, Wolff M, Bayer J, Wolz C, Greinacher A, Hammerschmidt S. \u03b1-hemolysin of Staphylococcus aureus impairs thrombus formation<\/strong>.\u00a0J Thromb Haemost. 2022 Mar 18. doi: 10.1111\/jth.15703. Epub ahead of print.\u00a0<\/span>PMID: 35303391.\u00a0https:\/\/pubmed.ncbi.nlm.nih.gov\/35303391\/<\/a><\/p>

Jahn K, Kohler TP, Swiatek LS, Wiebe S, Hammerschmidt S. Platelets, Bacterial Adhesins and the Pneumococcus<\/strong>. Cells. 2022 Mar 25;11(7):1121. doi: 10.3390\/cells11071121. PMID: 35406684; PMCID: PMC8997422.<\/a><\/p>

Jahn K*, Shumba P, Quach P, M\u00fcsken M, Wesche J, Greinacher A, Rajagopal L, Hammerschmidt S, Siemens N. Streptococcal hemolytic pigment impairs platelet function in a two-step process<\/strong>. Cells. 2022. doi: 10.3390\/cells11101637. PMID: 35626674.<\/a><\/p>

Komaragiri Y, Panhwar MH, Fregin B, Jagirdar G, Wolke C, Spiegler S, Otto O. Mechanical characterization of isolated mitochondria under conditions of oxidative stress<\/strong>. Biomicrofluidics. 2022. doi: 10.1063\/5.0111581. PMID: 36406339.<\/a><\/p>

Li P, Gawaz M, Chatterjee M, L\u00e4mmerhofer M. <\/span>Isomer-selective analysis of inositol phosphates with differential isotope labelling by phosphate methylation using liquid chromatography with tandem mass spectrometry<\/b>. Anal Chim Acta. 2022;1191:339286. <\/span>doi: 10.1016\/j.aca.2021.339286<\/span>. PMID: 35033253<\/span><\/a><\/p>

Lickert S, Kenny M, Selcuk K, Mehl JL, Bender M, Fr\u00fch SM, Burkhardt MA, Studt JD, Nieswandt B, Schoen I, Vogel V. Platelets drive fibronectin fibrillogenesis using integrin \u03b1IIb\u03b23<\/strong>. Sci Adv. 2022. doi: 10.1126\/sciadv.abj8331. PMID: 35275711.<\/a><\/p>

Michalik S, Siegerist F, Palankar R, Franzke K, Schindler M, Reder A, Seifert U, Cammann C, Wesche J, Steil L, Hentschker C, Gesell-Salazar M, Reisinger E, Beer M, Endlich N, Greinacher A, V\u00f6lker U. Comparative analysis of ChAdOx1 nCoV-19 and Ad26.COV2.S SARS-CoV-2 vector vaccines<\/strong>. Haematologica. 2022. doi: 10.3324\/haematol.2021.280154. PMID: 35045692.<\/a><\/p>

Nording H, Sauter M, Lin C, Steubing R, Geisler S, Sun Y, Niethammer, Emschermann, Wang Y, Zieger B, Nieswandt B, Kleinschnitz C, Simon DI, Langer H. Activated platelets upregulate \u03b22-integrin Mac-1 (CD11b\/CD18) on dendritic cells, which mediates heterotypic cell-cell interaction<\/strong>. J Immunol. 2022. doi: 10.4049\/jimmunol.2100557. PMID: 35277420.<\/a><\/p>

Palankar R*, Sachs L, Wesche J, Greinacher A. Cytoskeleton Dependent Mobility Dynamics of Fc\u03b3RIIA Facilitates Platelet Haptotaxis and Capture of Opsonized Bacteria<\/strong>. Cells. 2022. doi: 10.3390\/cells11101615. PMID: 35626650.<\/a><\/p>

Palma-Baqueros V*, Revilla N, Zaninetti C, Galera A, S\u00e1nchez-Fuentes A, Zamora-C\u00e1novas A, Bohdan N, Padilla J, Mar\u00edn-Quilez A, Rodriguez Alen A, Fuster J, Greinacher A, Vicente V, Bastida J, Rivera J, Lozano M. Src-related thrombocytopenia: a fine line between a megakaryocyte dysfunction and an immune-mediated disease<\/strong>. Blood Adv. 2022. doi: 10.1182\/bloodadvances.2021005446. PMID: 35349645.<\/a><\/p>

Rath D, Rapp V, Schwartz J, Winter S, Emschermann F, Arnold D, Rheinlaender J, B\u00fcttcher M, Strebl M, Braun MB, Altgelt K, Uribe \u00c1P, Schories C, Canjuga D, Schaeffeler E, Borst O, Sch\u00e4ffer TE, Langer H, Stehle T, Schwab M, Geisler T, Gawaz M, Chatterjee M. Homophilic Interaction Between Transmembrane-JAM-A and Soluble JAM-A Regulates Thrombo-Inflammation: Implications for Coronary Artery Disease<\/strong>. JACC Basic Transl Sci. 2022. doi: 10.1016\/j.jacbts.2022.03.003. PMID: 35663628.<\/a><\/p>

Reautschnig P, Wahn N, Wettengel J, Schulz AE, Latifi N, Vogel P, Kang TW, Pfeiffer LS, Zarges C, Naumann U, Zender L, Li JB, Stafforst T. CLUSTER guide RNAs enable precise and efficient RNA editing with endogenous ADAR enzymes in vivo<\/strong>. Nat Biotechnol. 2022. doi: 10.1038\/s41587-021-01105-0. PMID: 34980913.<\/a><\/p>

Rohlfing AK, Kolb K, Sigle M, Ziegler M, Bild A, M\u00fcnzer P, Sudmann J, Dicenta V, Harm T, Manke MC, Geue S, Kremser M, Chatterjee M, Liang C, von Eysmondt H, Dandekar T, Heinzmann D, G\u00fcnter M, von Ungern-Sternberg S, B\u00fcttcher M, Castor T, Mencl S, Langhauser F, Sies K, Ashour D, Beker MC, L\u00e4mmerhofer M, Autenrieth SE, Sch\u00e4ffer TE, Laufer S, Szklanna P, Maguire P, Heikenwalder M, M\u00fcller KAL, Hermann DM, Kilic E, Stumm R, Ramos G, Kleinschnitz C, Borst O, Langer HF, Rath D, Gawaz M. ACKR3 regulates platelet activation and ischemia-reperfusion tissue injury<\/strong>. Nat Commun. 2022. doi: 10.1038\/s41467-022-29341-1. PMID: 35383158.<\/a><\/p>

Rosa A, Butt E, Hopper CP, Loroch S, Bender M, Schulze H, Sickmann A, Vorlova S, Seizer P, Heinzmann D, Zernecke A. Cyclophilin A Is Not Acetylated at Lysine-82 and Lysine-125 in Resting and Stimulated Platelets<\/strong> Int J Mol Sci. 2022 Jan 27;23(3):1469. doi: 10.3390\/ijms23031469. PMID: 35163387; PMCID: PMC8836233.<\/a><\/p>

Sachs L, Wesche J, Lenkeit L, Greinacher A, Bender M, Otto O, Palankar R. <\/span>Ex vivo anticoagulants affect human blood platelet biomechanics with implications for high-throughput functional mechanophenotyping<\/b>.<\/span> Commun Biol. 2022 Jan 21;5(1):86. <\/span>
<\/span>doi: 10.1038\/s42003-021-02982-6. PMID: 35064207.<\/span><\/a><\/p>

Salih F*, Kohler S, Sch\u00f6nborn L, Thiele T, Greinacher A, Endres M. Early recognition and treatment of pre-VITT syndrome after adenoviral vector-based SARS-CoV-2 vaccination may prevent from thrombotic complications: review of published cases and clinical pathway<\/strong>. Eur Heart J Open. 2022. doi: 10.1093\/ehjopen\/oeac036. PMID: 35919343.<\/a><\/p>

Sauter M, Sauter RJ, Olbrich M, Thunemann M, Feil S, Feil R, Langer HF. Protocol to visualize CD11c+ cells in atherosclerosis using LacZ reporter mice<\/strong>. STAR Protoc. 2022. doi: 10.1016\/j.xpro.2022.101645. PMID: 36042879.<\/a><\/p>

Scheller I, Beck S, G\u00f6b V, Gross C, Neagoe RAI, Aurbach K, Bender M, Stegner D, Nagy Z, Nieswandt B. Thymosin beta4 is essential for thrombus formation by controlling the G-actin\/F-actin equilibrium in platelets<\/strong>. Haematologica. 2022. doi: 10.3324\/haematol.2021.278537. PMID: 34348450.<\/a><\/p>

Sch\u00f6nborn L*, Seck S, Thiele T, Warkentin T, Greinacher A. SARS-CoV-2 Infection in Patients with a History of VITT<\/strong>. N Engl J Med. 2022. doi: 10.1056\/NEJMc2206601. PMID: 35759529.<\/a><\/p>

Sch\u00f6nborn L*, Thiele T, Esefeld M, El Debuch K, Wesche J, Seck S, Kaderali L, Wolff M, Warkentin T, Greinacher A. Quantitative Interpretation of PF4\/Heparin-EIA Optical Densities in Predicting for Platelet-Activating VITT Antibodies<\/strong>. J Thromb Haemost. 2022. doi: 10.1111\/jth.15862. PMID: 36006172.<\/a><\/p>

Sch\u00f6nborn L*, Thiele T, Kaderali L, Guenther A, Hoffmann T, Seck S, Selleng K, Greinacher A. Most Anti-PF4 Antibodies in Vaccine-induced Immune Thrombotic Thrombocytopenia are transient<\/strong>. Blood. 2022. doi: 10.1182\/blood.2021014214. PMID: 35113987.<\/a><\/p>

Stegner D, G\u00f6b V, Krenzlin V, Beck S, Hemmen K, Schuhmann MK, Sch\u00f6rg B, Hackenbroch C, May F, Burkard P, Pinnecker J, Zernecke A, Rosenberger P, Greinacher A, Pichler BJ, Heinze KG, Stoll G, Nieswandt B.<\/i>\u00a0Foudroyant cerebral venous (sinus) thrombosis triggered through CLEC-2 and GPIIb\/IIIa dependent platelet activation.<\/b>\u00a0Nat Cardiovasc Res\u00a01,\u00a0<\/b>132\u2013141 (2022).\u00a0https:\/\/doi.org\/10.1038\/s44161-021-00017-1<\/span><\/a><\/p>

Stoll G, Schuhmann MK, Nieswandt B, Kollikowski AM, Pham M. An intravascular perspective on hyper-acute neutrophil, T-cell and platelet responses: Similarities between human and experimental stroke<\/strong>. J Cereb Blood Flow Metab. 2022. doi: 10.1177\/0271678X221105764. PMID: 35676801.<\/a><\/p>

Thiele T*, Weisser K, Sch\u00f6nborn L, Funk M, Weber G, Greinacher A, Keller-Stanislawski B. Laboratory confirmed vaccine-induced immune thrombotic thrombocytopenia: Retrospective analysis of reported cases after vaccination with ChAdOx-1 nCoV-19 in Germany<\/strong>. Lancet Reg Health Eur. 2022. doi: 10.1016\/j.lanepe.2021.100270. PMID: 34901912.<\/a><\/p>

Thiele T, Schwarz SL, Handtke S. Platelet size as a mirror for the immune response after SARS-CoV-2 vaccination<\/strong>.J Thromb Haemost. 2022. doi: 10.1111\/jth.15659. PMID: 35156282.<\/a><\/p>

Tian Y, Yang S, Nagel G, Gao S. Characterization and Modification of Light-Sensitive Phosphodiesterases from Choanoflagellates<\/strong>. Biomolecules. 2022. doi: 10.3390\/biom12010088. PMID: 35053236.<\/a><\/p>

Vayne C*, Palankar R, Billy S, Handtke S, Thiele T, Cordonnier C, Pouplard C, Greinacher A, Gruel Y, Rollin J. The deglycosylated form of 1E12 inhibits platelet activation and prothrombotic effects induced by VITT antibodies<\/strong>. Haematologica. 2022. doi: 10.3324\/haematol.2021.280251. PMID: 35385923.<\/a><\/p>

Veninga A*, Handtke S, Aurich K, Tullemans B, Brouns S, Schwarz S, Heubel-Moenen F, Greinacher A, Heemskerk J, van der Meijden P, Thiele T. GPVI expression is linked to platelet size, age, and reactivity<\/strong>. Blood Adv. 2022. doi: 10.1182\/bloodadvances.2021006904. PMID: 35561312.<\/a><\/p>

Weiss LJ, Drayss M, Mott K, Droste M, Just B, Arold AM, Nieswandt B, Weismann D, Stegner D, Schulze H. The homophilic CD84 receptor is upregulated on platelets in COVID-19 sepsis<\/strong>. Thromb Res. 2022. doi: 10.1016\/j.thromres.2022.10.011. PMID: 36334399.<\/a><\/p>

Wichers JS, Mes\u00e9n-Ram\u00edrez P, Fuchs G, Yu-Strzelczyk J, St\u00e4cker J, von Thien H, Alder A, Henshall I, Liffner B, Nagel G, L\u00f6w C, Wilson D, Spielmann T, Gao S, Gilberger TW, Bachmann A, Strauss J. PMRT1, a Plasmodium-Specific Parasite Plasma Membrane Transporter, Is Essential for Asexual and Sexual Blood Stage Development<\/strong>. mBio. 2022. doi: 10.1128\/mbio.00623-22. PMID: 35404116.<\/a><\/p>

Wolf R*, Grammbauer S, Palankar R, Tolksdorf C, Moritz E, B\u00f6hm A, Hasan M, Hafkemeyer A, Greinacher A, Tzvetkov M, Rauch B, Jedlitschky G. Specific inhibition of the transporter MRP4\/ABCC4 affects multiple signaling pathways and thrombus formation in human platelets<\/strong>. Haematologica. 2022. doi: 10.3324\/haematol.2021.279761. PMID: 35295075.<\/a><\/p>

Zdanyte M, Martus P, Nestele J, Bild A, Mizera L, Glatthaar A, Petersen Uribe \u00c1, Emschermann F, Henes JK, Geisler T, M\u00fcller K, Gawaz M, Rath D. Risk assessment in COVID-19: Prognostic importance of cardiovascular parameters<\/strong>. Clin Cardiol. 2022. doi: 10.1002\/clc.23883. PMID: 35789499.<\/a><\/p>

Zdanyte M, Rath D, Gawaz M, Geisler T. Venous Thrombosis and SARS-CoV-2<\/strong>. Hamostaseologie. 2022. doi: 10.1055\/a-1661-0283. PMID: 34879422.<\/a><\/p>

Zhang Y, Benz P, Stehle D, Yang S, Kurz H, Feil S, Nagel G, Feil R, Gao S, Bender M. 2022.\u00a0Optogenetic manipulation of cyclic guanosine monophosphate to probe phosphodiesterase activities in megakaryocytes.<\/strong>\u00a0Open Biol<\/em>\u00a012, 220058. doi: 10.1098\/rsob.220058.<\/span><\/a><\/p>

Zimmermann L*, Pham M*, M\u00e4rz AG, Kollikowski AM, Stoll G, Schuhmann MK. Defining cerebral leukocyte populations in local ischemic blood samples from patients with hyperacute stroke<\/strong>. J Cereb Blood Flow Metab. 2022. doi: 10.1177\/0271678X221078617. PMID: 35107055.<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

\n\t\t\t\t
\n\t\t\t\t\t

2021<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t\t\t

Althaus K, Marini I, Zlamal J, Pelzl L, Singh A, H\u00e4berle H, Mehrl\u00e4nder M, Hammer S, Schulze H, Bitzer M, Malek N, Rath D, B\u00f6sm\u00fcller H, Nieswandt B, Gawaz M, Bakchoul T, Rosenberger P. Antibody-induced procoagulant platelets in severe COVID-19 infection<\/strong>. Blood. 2021;137(8):1061-1071.
DOI: 10.1182\/blood.2020008762<\/a><\/p>

Beck S, Stegner D, Loroch S, Baig AA, G\u00f6b V, Schumbrutzki C, Eilers E, Sickmann A, May F, Nolte MW, Panousis C, Nieswandt B. <\/span>Generation of a humanized FXII knock-in mouse-A powerful model system to test novel anti-thrombotic agents<\/b>. <\/span>J Thromb Haemost. 2021 Nov;19(11):2835-2840. <\/span>
<\/span>doi: 10.1111\/jth.15488. Epub 2021 Aug 19. PMID: 34363738.<\/span><\/a><\/p>

Bender M, Palankar R.\u00a0Platelet Shape Changes during Thrombus Formation: Role of Actin-Based Protrusions<\/b>.\u00a0Hamostaseologie. 2021 Feb;41:14-21.
doi: 10.1055\/a-1325-0993. Epub 2021 Feb 15.<\/a><\/p>

Bieber M, Schuhmann MK, Kollikowski AM, Stegner D, Nieswandt B, Pham M, Stoll G. <\/span>Targeting platelet glycoprotein VI attenuates progressive ischemic brain damage before recanalization during middle cerebral artery occlusion in mice.<\/b> Exp Neurol. 2021 Oct; 344:113804. <\/span>
<\/span>doi: 10.1016\/j.expneurol.2021.113804. Epub 2021 Jul 6. PMID: 34237320.<\/span><\/a><\/p>

Cebo M, Dittrich K, Fu X, Manke MC, Emschermann F, Rheinlaender J, von Eysmondt H, Ferreir\u00f3s N, Sudmann-Innerhofer J, Witte A, Pelzl L, Borst O, Geisler T, Rath D, Bakchoul T, Gawaz M, Sch\u00e4ffer TEE, L\u00e4mmerhofer M, Chatterjee M. <\/span>Platelet ACKR3\/CXCR7 Favors Anti-Platelet Lipids over an Atherothrombotic Lipidome and Regulates Thrombo-inflammation<\/b>. Blood. 2021 Dec 14:blood.2021013097. <\/span>doi: 10.1182\/blood.2021013097<\/span>. PMID: 34905596\u00a0<\/span><\/a>
<\/a><\/p>

Cebo M, Calder\u00f3n Castro C, Schlotterbeck J, Gawaz M, Chatterjee M, L\u00e4mmerhofer M. <\/span>Untargeted UHPLC-ESI-QTOF-MS\/MS analysis with targeted feature extraction at precursor and fragment level for profiling of the platelet lipidome with ex vivo thrombin-activation<\/b>. J Pharm Biomed Anal. 2021;205:114301. <\/span>doi: 10.1016\/j.jpba.2021.114301<\/span>. PMID: 34391135<\/span><\/a><\/p>

Chatterjee M. <\/span>Atypical Roles of the Chemokine Receptor ACKR3\/CXCR7 in Platelet Pathophysiology<\/b>. Cells. 2022. <\/span>doi: 10.3390\/cells11020213<\/span>. PMID: 35053329<\/span><\/a><\/p>

Essig F, Kollikowski AM, M\u00fcllges W, Stoll G, Haeusler KG, Schuhmann MK, Pham M. Local Cerebral Recombinant Tissue Plasminogen Activator Concentrations During Acute Stroke. <\/strong>JAMA Neurol. 2021 May 1;78(5):615-617.
doi: 10.1001\/jamaneurol.2021.0065. PMID: 33683294; PMCID: PMC7941250.<\/a><\/p>

Feil R, Lehners M, Stehle D, Feil S.\u00a0Visualising and understanding cGMP signals in the cardiovascular\u00a0system<\/span>. Br J Pharmacol. 2021 Apr 20.
doi: 10.1111\/bph.15500<\/a><\/p>

Franke M, Bieber M, Kraft P, Weber ANR, Stoll G, Schuhmann MK. The NLRP3 inflammasome drives inflammation in ischemia\/reperfusion injury after transient middle cerebral artery occlusion in mice<\/strong>. Brain Behav Immun. 2021 Feb;92:223-233. doi: 10.1016\/j.bbi.2020.12.009. Epub 2020 Dec 9. PMID: 33307174.<\/a><\/p>

Franke M, Bieber M, Stoll G, Schuhmann MK. Validity and Efficacy of Methods to Define Blood Brain Barrier Integrity in Experimental Ischemic Strokes: A Comparison of Albumin Western Blot, IgG Western Blot and Albumin Immunofluorescence<\/strong>. Methods Protoc. 2021 Mar 23;4(1):23.
doi: 10.3390\/mps4010023. PMID: 33806760; PMCID: PMC8005953.<\/a><\/p>

G\u00f6b V, Voll MG, Zimmermann L, Hemmen K, Stoll G, Nieswandt B, Schuhmann MK, Heinze KG, Stegner D. <\/span>Infarct growth precedes cerebral thrombosis following experimental stroke in mice<\/b>. <\/span>Sci Rep. 2021 Nov 24;11(1):22887. <\/span>
<\/span>doi: 10.1038\/s41598-021-02360-6. PMID: 34819574.<\/span><\/a><\/p>

Hammer S, H\u00e4berle H, Schlensak C, Bitzer M, Malek NP, Handgretinger R, Lang P, H\u00f6rber S, Peter A, Martus P, Mirakaj V, Gawaz M, Geisler T, Althaus K, Rosenberger P, Bakchoul T. Severe SARS-CoV-2 Infection Inhibits Fibrinolysis Leading to Changes in Viscoelastic Properties of Blood Clot: A Descriptive Study of Fibrinolysis in COVID-19<\/strong>. Thromb Haemost. 2021 Feb 25. Online ahead of print.
doi: 10.1055\/a-1400-6034. PMID: 33634444<\/a><\/p>

Harm T, Bild A, Dittrich K, Goldschmied A, Nestele J, Chatterjee M, Fu X, Kolb, K, Castor T, Borst O, Geisler T, Rath D, L\u00e4mmerhofer M, Gawaz M. <\/span>Acute coronary syndrome is associated with a substantial change in the platelet lipidome<\/b>. Cardiovasc Res. 2021. <\/span>doi: 10.1093\/cvr\/cvab238<\/span>. PMID: 34323932<\/span><\/a><\/p>

Heib T, Herrmans J, Manukjan G, Englert M, Kusch C, Becker IC, Gerber A, Wackerbarth LM, Burkhard P, Dandekar T, Balkenhol J, Jahn D, Beck S, Meub M, D\u00fctting S, Stigloher C, Sauer M, Cherpokova D, Schulze H, Brakebusch C, Nieswandt B, Nagy Z, and Pleines I. RhoA\/Cdc42 signaling drives cytoplasmic maturation but not endomitosis in megakaryocytes<\/strong>. Cell Reports, 2021; 35(6):109102.
doi: 10.1016\/j.celrep.2021.109102. PMID: 33979620<\/a><\/p>

Henes JK, Groga-Bada P, Schaeffeler E, Winter S, Hack L, Zdanyte M, Mueller K, Droppa M, Stimpfle F, Gawaz M, Langer H, Schwab M, Geisler T, Rath D. C5 Variant rs10985126 is Associated with Mortality in Patients with Symptomatic Coronary Artery Disease<\/strong>. Pharmgenomics Pers Med. 2021 Jul 21;14:893-903.
doi: 10.2147\/PGPM.S307827. eCollection 2021. PMID: 34321906<\/a><\/p>

Hinterleitner C, Zhou Y, Tandler C, Heitmann JS, Kropp KN, Hinterleitner M, Koch A, Hartkopf AD, Zender L, Salih HR, Maurer S. 2021. Platelet-Expressed TNFRSF13B (TACI) Predicts Breast Cancer Progression<\/strong>. Front Oncol. 2021 Mar 17;11:642170.
doi: 10.3389\/fonc.2021.642170<\/a><\/p>

Hinterleitner M, Sipos B, Wagner V, Grottenthaler JM, Lauer UM, Zender L, Hinterleitner C. 2021 Platelet-Expressed Synaptophysin (pSyn) as Novel Biomarker in Neuroendocrine Malignancies<\/strong>. Cancers (Basel). 2021 May 11;13(10):2286.
doi: 10.3390\/cancers13102286.<\/a><\/p>

Kollikowski AM, Pham M, M\u00e4rz AG, Papp L, Nieswandt B, Stoll G, Schuhmann MK. <\/span>Platelet Activation and Chemokine Release Are Related to Local Neutrophil-Dominant Inflammation During Hyperacute Human Stroke<\/b>. <\/span>Transl Stroke Res. 2021 Aug 28. <\/span>
<\/span>doi: 10.1007\/s12975-021-00938-w. Online ahead of print. PMID: 34455571.<\/span><\/a><\/p>

Kollikowski AM, Cattus F, Haag J, Feick J, M\u00e4rz AG, Weidner F, Schuhmann MK, M\u00fcllges W, Stoll G, Pham M, Strinitz M. Progression of cerebral infarction before and after thrombectomy is modified by prehospital pathways<\/strong>. J Neurointerv Surg. 2021 May 13:neurintsurg-2020-017155.
doi: 10.1136\/neurintsurg-2020-017155. Epub ahead of print. PMID: 33986107.<\/a><\/p>

Langnau C, Rohlfing AK, Gekeler S, G\u00fcnter M, P\u00f6schel S, Petersen-Uribe \u00c1, Jaeger P, Avdiu A, Harm T, Kreisselmeier KP, Castor T, Bakchoul T, Rath D, Gawaz MP, Autenrieth SE, Mueller KAL. Platelet Activation and Plasma Levels of Furin Are Associated With Prognosis of Patients With Coronary Artery Disease and COVID-19<\/strong>. Arterioscler Thromb Vasc Biol. 2021;41(6):2080-2096.
DOI: 10.1161\/ATVBAHA.120.315698<\/a><\/p>

Li P, Gawaz M, Chatterjee M, L\u00e4mmerhofer M. 2021 Targeted Profiling of Short-, Medium-,\u00a0and Long-Chain Fatty Acyl-Coenzyme As in Biological Samples by Phosphate Methylation\u00a0Coupled to Liquid Chromatography-Tandem Mass Spectrometry<\/b>. 2021. Anal Chem. 93:4342-4350.<\/a><\/p>

Li P, L\u00e4mmerhofer M. <\/span>Isomer Selective Comprehensive Lipidomics Analysis of Phosphoinositides in Biological Samples by Liquid Chromatography with Data Independent Acquisition Tandem Mass Spectrometry<\/b>. Anal Chem. 2021;93(27):9583-92. <\/span>doi: 10.1021\/acs.analchem.1c01751<\/span>. PMID: 34191474<\/span><\/a><\/p>

Manke MC, Geue S, Coman C, Peng B, Kollotzek F, M\u00fcnzer P, Walker B, Huber SM, Rath D, Sickmann A, Stegner D, Duerschmied D, Lang F, Nieswandt B, Gawaz M, Ahrends R, Borst O. <\/span>ANXA7 Regulates Platelet Lipid Metabolism and Ca<\/b>2+<\/b> Release in Arterial Thrombosis<\/b>. <\/span>Circ Res. 2021 Aug 6;129(4):494-507. <\/span>
<\/span>doi: 10.1161\/CIRCRESAHA.121.319207. Epub 2021 Jun 28. PMID: 34176316.<\/span><\/a><\/p>

Mueller KAL, Jorbenadze R, Gawaz M, Schreieck J, Seizer P. „Mind the Gap“: An 85-Year-Old Man with Severe Tricuspid Valve Regurgitation Who Underwent Percutaneous Edge-to-Edge Valve Leaflet Plication Using the New and Advanced MitraClip XTR System<\/strong>. Am J Case Rep. 2021;22:e928089. doi: 10.12659\/AJCR.928089. PMID: 33456048<\/a><\/p>

Mueller KAL, Langnau C, G\u00fcnter M, P\u00f6schel S, Gekeler S, Petersen-Uribe \u00c1, Kreisselmeier KP, Klingel K, B\u00f6sm\u00fcller H, Li B, Jaeger P, Castor T, Rath D, Gawaz MP, Autenrieth SE. Numbers and phenotype of non-classical CD14dimCD16+ monocytes are predictors of adverse clinical outcome in patients with coronary artery disease and severe SARS-CoV-2 infection<\/strong>. Cardiovasc Res. 2021;117(1):224-239.
DOI: 10.1093\/cvr\/cvaa328<\/a><\/p>

M\u00fcller II, Schneider M, M\u00fcller KAL, Lunov O, Borst O, Simmet T, Gawaz M. Protective role of Gremlin-1 in myocardial function<\/strong>. Eur J Clin Invest. 2021;51(7):e13539.
DOI: 10.1111\/eci.13539<\/a><\/p>

Nording H, Baron L, Haberth\u00fcr D, Emschermann F, Mezger M, Sauter M, Sauter R, Patzelt J, Knoepp\u00a0K, Nording A, Meusel M, Meyer-Saraei R, Hlushchuk R, Sedding D, Borst O, Eitel I, Karsten CM, Feil R,\u00a0Pichler B, Erdmann J, Verschoor A, Chavakis E, Chavakis T, von Hundelshausen P, K\u00f6hl J, Gawaz M,\u00a0Langer HF. The C5a\/C5a receptor 1 axis controls tissue neovascularization through CXCL4 release\u00a0from platelets<\/b>. Nat Commun. 2021 Jun 7;12(1):3352.
doi: 10.1038\/s41467-021-23499-w<\/a><\/p>

Petersen-Uribe A, Avdiu A, Martus P, Witzel K, Jaeger P, Zdanyte M, Heinzmann D, Tavlaki E, Warm V, Geisler T, M\u00fcller K, Gawaz M, Rath D. Impaired Myocardial Function Is Prognostic for Severe Respiratory Failure in the Course of COVID-19 Infection<\/strong>. Front Cardiovasc Med. 2021;8:584108.
DOI: 10.3389\/fcvm.2021.584108<\/a><\/p>

Scheller I, Beck S, G\u00f6b V, Gross C, Neagoe RAI, Aurbach K, Bender M, Stegner D, Nagy Z, Nieswandt B. <\/span>Thymosin \u03b24 is essential for thrombus formation by controlling the G-actin\/F-actin equilibrium in platelets<\/b>. <\/span>Haematologica. 2021 Aug 5. <\/span>
<\/span>doi: 10.3324\/haematol.2021.278537. Online ahead of print. PMID: 34348450.<\/span><\/a><\/p>

Schuhmann MK, Bieber M, Franke M, Kollikowski AM, Stegner D, Heinze KG, Nieswandt B, Pham M, Stoll G. Platelets and lymphocytes drive progressive penumbral tissue loss during middle cerebral artery occlusion in mice<\/strong>. J Neuroinflammation. 2021 Feb 18;18(1):46.
doi: 10.1186\/s12974-021-02095-1. PMID: 33602266; PMCID: PMC7890632.<\/a><\/p>

Seifert J, von Eysmondt H, Chatterjee M, Gawaz M, Sch\u00e4ffer TE. <\/span>Effect of Oxidized LDL on Platelet Shape, Spreading, and Migration Investigated with Deep Learning Platelet Morphometry<\/b>. Cells. 2021;10(11):2932. <\/span>doi: 10.3390\/cells10112932<\/span>. PMID: 34831155<\/span><\/a><\/p>

Seyhan M, Ungeth\u00fcm K, Schuhmann MK, Mackenrodt D, R\u00fccker V, Montellano FA, Wiedmann S, Rath D, Geisler T, Nieswandt B, Kraft P, Kleinschnitz C, Heuschmann PU.<\/span>Feasibility of platelet marker analysis in ischemic stroke patients and their association with one-year outcome. A pilot project within a subsample of the Stroke Induced Cardiac Failure in Mice and Men (SICFAIL) cohort study.<\/b> Platelets. 2021 Dec 7:1-9. <\/span>
<\/span>doi: 10.1080\/09537104.2021.2002834. Online ahead of print. PMID: 34875957.<\/span><\/a><\/p>

Stehle D, Xu MZ, Schomber T, Hahn MG, Schweda F, Feil S, Kraehling JR, Eitner F, Patzak A, Sandner P,\u00a0Feil R, Benardeau A. Novel sGC activators increase glomerular cGMP, induce vasodilation, and\u00a0improve blood flow in the murine kidney<\/b>. Br J Pharmacol. 2021 Jun 7.doi: 10.1111\/bph.15586<\/a><\/p>

Tchernychev B, Li H, Lee SK, Gao X, Ramanarasimhaiah R, Liu G, Hall KC, Bernier SG, Jones JE, Feil S,\u00a0Feil R, Buys ES, Graul RM, Frenette PS, Masferrer JL. Olinciguat, a stimulator of soluble guanylyl\u00a0cyclase, attenuates inflammation, vaso-occlusion and nephropathy in mouse models of sickle cell\u00a0disease<\/b>. Br J Pharmacol. 2021 Apr 17.doi: 10.1111\/bph.15492<\/a><\/p>

Wagner N*, Mott K*, Upcin B, Stegner D, Schulze H*, Erg\u00fcn S. CXCL12-abundant reticular (CAR) cells direct megakaryocyte protrusions across the bone marrow sinusoid wall<\/strong>. Cells 2021; 10, 722.
PMID: 33804965<\/a><\/p>

Weiss L, Manukjan G, Pflug A, Winter N, Weigel M, Nagler N, Kredel M, Lam T-T, Nieswandt B, Weismann D, Schulze H. Acquired platelet GPVI receptor dysfunction in critically-ill patients with sepsis<\/strong>. Blood 2021; 137(22):3105-15.
PMID: 33827131<\/a><\/p>

Witte A, Rohlfing AK, Dannenmann B, Dicenta V, Nasri M, Kolb K, Sudmann J, Castor T, Rath D, Borst O, Skokowa J, Gawaz M. The chemokine CXCL14 mediates platelet function and migration via direct interaction with CXCR4<\/strong>. Cardiovasc Res. 2021;117(3):903-917.
DOI: 10.1093\/cvr\/cvaa080<\/a><\/p>

Zhou L, Heitmann JS, Clar KL, Kropp KN, Hinterleitner M, Koch A, Hartkopf A, Zender L, Salih HR, Maurer S, Hinterleitner C. 2021. Platelet-expressed immune checkpoint regulator GITRL in breast cancer<\/strong>. Cancer Immunol Immunother. 2021 Feb 4.
doi: 10.1007\/s00262-021-02866-y<\/a><\/p>

Zhou K, Zhu X, Ma K, Liu J, N\u00fcrnberg B, Gawaz M, Lang F. Effect of MgCl 2 and GdCl 3 on ORAI1 Expression and Store-Operated Ca 2+ Entry in Megakaryocytes<\/strong>. Int J Mol Sci. 2021 Mar 24;22(7):3292.
doi: 10.3390\/ijms22073292. PMID: 33804889<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

\n\t\t\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t

2020<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t\t\t

Balkenhol J, Kaltdorf KV, Mammadova-Bach E, Braun A, Nieswandt B, Dittrich M, Dandekar\u00a0T. 2020. Comparison of the central human and mouse platelet signaling cascade by systems\u00a0biological analysis<\/b>. BMC Genomics 21(1):897.<\/a><\/p>

B\u00e4cher C, Bender M, Gekle S.\u00a0Flow-accelerated platelet biogenesis is due to an elasto-hydrodynamic instability<\/b>.\u00a0Proc Natl Acad Sci U S A. 2020 Aug 11;117(32):18969-18976.
doi: 10.1073\/pnas.2002985117. Epub 2020 Jul 27.<\/a><\/p>

Becker IC, Scheller I, Wackerbarth LM, et al. Actin\/microtubule crosstalk during platelet biogenesis in mice is critically regulated by Twinfilin1 and Cofilin1. Blood<\/strong> Adv. 2020;4(10):2124-2134.
doi:10.1182\/bloodadvances.2019001303<\/a><\/p>

Cebo M, Fu X, Gawaz M, Chatterjee M, L\u00e4mmerhofer M. 2020 Micro-UHPLC-MS\/MS\u00a0method for analysis of oxylipins in plasma and platelets. J Pharm Biomed Anal<\/b>. 10;\u00a0189:113426.<\/a><\/p>

Cebo M, Fu X, Gawaz M, Chatterjee M, L\u00e4mmerhofer M. 2020 Enantioselective ultra-high-performance liquid chromatography-tandem mass spectrometry method based on sub-2\u00b5m\u00a0particle polysaccharide column for chiral separation of oxylipins and its application for the\u00a0analysis of autoxidized fatty acids and platelet releasates<\/b>. J Chromatogr A. 1624:461206.<\/a><\/p>

Chatterjee M. Platelet lipidome: Dismantling the „Trojan horse“ in the bloodstream<\/strong>. J Thromb Haemost. 2020;18(3):543-557.
doi:10.1111\/jth.14721<\/a><\/p>

Colberg L, Cammann C, Greinacher A, Seifert U. Structure and function of the ubiquitin-proteasome system in platelets<\/strong>. J Thromb Haemost. 2020;18(4):771-780.
doi:10.1111\/jth.14730<\/a><\/p>

Cullmann K, Jahn M, Spindler M, Schenk F, Manukjan G, Mucci A, Steinemann D, Boller K, Schulze H, Bender M, Moritz T, Modlich U.\u00a0Forming megakaryocytes from murine-induced pluripotent stem cells by the inducible overexpression of supporting factors<\/b>.\u00a0Res Pract Thromb Haemost. 2020 Dec 3;5:111-124. doi: 10.1002\/rth2.12453. eCollection 2021 Jan.<\/a><\/p>

Eekels JJM, Pachler C, Krause N, Muhr T, Waltl G, Greinacher A. Ticagrelor causes false-negative functional tests for heparin-induced thrombocytopenia<\/strong>. Blood. 2020;135(11):875-878.
doi:10.1182\/blood.2019003582<\/a><\/p>

Essig F, Kollikowski AM, Pham M, Solymosi L, Stoll G, Haeusler KG, Kraft P, Schuhmann MK. Immunohistological Analysis of Neutrophils and Neutrophil Extracellular Traps in Human Thrombemboli Causing Acute Ischemic Stroke<\/strong>. Int J Mol Sci. 2020 Oct 7;21(19):7387. <\/a>
doi: 10.3390\/ijms21197387. PMID: 33036337; PMCID: PMC7582743.<\/a><\/p>

Gorelashvili MG, Angay O, Hemmen K, Klaus V, Stegner D, Heinze KG. Megakaryocyte volume modulates bone marrow niche properties and cell migration dynamics<\/strong>. Haematologica. 2020;105(4):895-904.<\/a><\/p>

doi:10.3324\/haematol.2018.202010<\/a><\/p>

Green HLH, Zuidscherwoude M, Alenazy F, Smith CW, Bender M, Thomas SG.\u00a0SMIFH2 inhibition of platelets demonstrates a critical role for formin proteins in platelet cytoskeletal dynamics<\/b>.\u00a0J Thromb Haemost. 2020 Jan 13.
doi: 10.1111\/jth.14735. [Epub ahead of print]<\/a><\/p>

Heinzmann D, Noethel M, Ungern-Sternberg SV, Mitroulis I, Gawaz M, Chavakis T, May AE, Seizer P. CD147 is a Novel Interaction Partner of Integrin \u03b1M\u03b22 Mediating Leukocyte and Platelet Adhesion<\/strong>.<\/a> Biomolecules 2020; 10(4):541.<\/a>
DOI: 10.3390\/biom10040541<\/p>

Jahn K, Handtke S, Palankar R, Wei\u00dfm\u00fcller S, Nouailles G, Kohler TP, Wesche J, Rohde M, Heinz C, Aschenbrenner AF, Wolff M,\u00a0 Sch\u00fcttrumpf J, Witzenrath M, Hammerschmidt S*, Greinacher A*. 2020. Pneumolysin induces platelet destruction, not platelet activation, which can be prevented by immunoglobulin preparations in vitro<\/strong>. Blood Adv 4 (24): 6315\u20136326.
doi: 10.1182\/bloodadvances.2020002372\u00a0<\/a><\/p>

Kollikowski AM, Schuhmann MK, Nieswandt B, M\u00fcllges W, Stoll G, Pham M. Local Leukocyte Invasion during Hyperacute Human Ischemic Stroke<\/strong>. Ann Neurol. 2020 Mar;87(3):466-479.
doi: 10.1002\/ana.25665. Epub 2020 Jan 16. PMID: 31899551.<\/a><\/p>

K\u00f6hler D, Granja T, Volz J, et al. Red blood cell-derived semaphorin 7A promotes thrombo-inflammation in myocardial ischemia-reperfusion injury through platelet GPIb<\/strong>. Nat Commun. 2020;11(1):1315. Published 2020 Mar 11.<\/a>
doi:10.1038\/s41467-020-14958-x<\/a><\/p>

Levi M, Epshtein M, Castor T, Gawaz M, Korin N. Glycoprotein VI (GPVI)-functionalized nanoparticles targeting arterial injury sites under physiological flow<\/strong>. Nanomedicine. 2020;29:102274.<\/a>
DOI: 10.1016\/j.nano.2020.102274<\/a><\/p>

Maguire PB, Parsons ME, Szklanna PB, Zdanyte M, M\u00fcnzer P, Chatterjee M, Wynne K, Rath D, Comer SP, Hayden M, N\u00ed \u00c1inle F, Gawaz M. Comparative Platelet Releasate Proteomic Profiling of Acute Coronary Syndrome versus Stable Coronary Artery Disease<\/strong>. Front Cardiovasc Med. 2020;7:101.
DOI: 10.3389\/fcvm.2020.00101<\/a><\/p>

Mammadova-Bach E, Gil-Pulido J, Sarukhanyan E, et al. Platelet glycoprotein VI promotes metastasis through interaction with cancer cell-derived galectin-3<\/strong>. Blood. 2020;135(14):1146-1160.
doi:10.1182\/blood.2019002649<\/a><\/p>

Nguyen TH, Xu Y, Brandt S, et al. Characterization of the interaction between platelet factor 4 and homogeneous synthetic low molecular weight heparins<\/strong>. J Thromb Haemost. 2020;18(2):390-398.
doi:10.1111\/jth.14657<\/a><\/p>

Nicolai L, Schiefelbein K, Lipsky S, Leunig A, Hoffknecht M, Pekayvaz K, Raude B, Marx C, Ehrlich A, Pircher J, Zhang Z, Saleh I, Marel AK, L\u00f6f A, Petzold T, Lorenz M, Stark K, Pick R, Rosenberger G, Weckbach L, Uhl B, Xia S, Reichel CA, Walzog B, Schulz C, Zheden V, Bender M, Li R, Massberg S, Gaertner F.\u00a0Vascular surveillance by haptotactic blood platelets in inflammation and infection<\/b>.\u00a0Nat Commun 2020 Nov 13;11:5778.
doi: 10.1038\/s41467-020-19515-0.<\/a><\/p>

Pelzl L, Sahu I, Ma K, Heinzmann D, Bhuyan AAM, Al-Maghout T, Sukkar B, Sharma Y, Marini I, Rigoni F, Artunc F, Cao H, Gutti R, Voelkl J, Pieske B, Gawaz M, Bakchoul T, Lang F. Beta-Glycerophosphate-Induced ORAI1 Expression and Store Operated Ca2+ Entry in Megakaryocytes<\/strong>. Sci Rep 2020;10:1728.
DOI: 10.1038\/s41598-020-58384-x<\/a><\/p>

Peng B, Kopczynski D, Pratt BS, Ejsing CS, Burla B, Hermansson M, Benke PI, Tan SH, Chan MY, Torta F, Schwudke D, Meckelmann SW, Coman C, Schmitz OJ, MacLean B, Manke MC, Borst O, Wenk MR, Hoffmann N, Ahrends R. LipidCreator workbench to probe the lipidomic landscape<\/b>. Nat Commun. 2020:11(1):2057.
DOI: 10.1038\/s41467-020-15960-z<\/a><\/p>

Rath D, Petersen-Uribe \u00c1, Avdiu A, Witzel K, Jaeger P, Zdanyte M, Heinzmann D, Tavlaki E, M\u00fcller K, Gawaz MP. Impaired cardiac function is associated with mortality in patients with acute COVID-19 infection<\/strong>. Clin Res Cardiol 2020; 109(12): 1491-1499;
DOI: 10.1007\/s00392-020-01683-0<\/a><\/p>

Rath D, von Ungern-Sternberg S, Heinzmann D, et al. Platelet surface expression of cyclophilin A is associated with increased mortality in patients with symptomatic coronary artery disease<\/strong>. J Thromb Haemost. 2020;18(1):234-242.
doi:10.1111\/jth.14635<\/a><\/p>

Rheinlaender J and T.E. Sch\u00e4ffer.\u00a0The effect of finite sample thickness in scanning ion conductance microscopy stiffness measurements.<\/span><\/a>
Applied Physics Letters 117, 113701 (2020)<\/a><\/p>

Scheller I, Stritt S, Beck S, et al. Coactosin-like 1 integrates signaling critical for shear-dependent thrombus formation in mouse platelets<\/strong>. Haematologica. 2020;105(6):1667-1676.
doi:10.3324\/haematol.2019.225516<\/a><\/p>

Schneider F, Horowitz A, Lesch KP, Dandekar T. Delaying memory decline: different options and emerging solutions<\/strong>. Transl Psychiatry. 2020;10(1):13. Published 2020 Jan 21.
doi:10.1038\/s41398-020-0697-x<\/a><\/p>

Schuhmann MK, Stoll G, Bieber M, V\u00f6gtle T, Hofmann S, Klaus V, Kraft P, Seyhan M, Kollikowski AM, Papp L, Heuschmann PU, Pham M, Nieswandt B, Stegner D. CD84 Links T Cell and Platelet Activity in Cerebral Thrombo-Inflammation in Acute Stroke<\/strong>. Circ Res. 2020 Sep 25;127(8):1023-1035.
doi: 10.1161\/CIRCRESAHA.120.316655. Epub 2020 Jul 30. PMID: 32762491; PMCID: PMC7508294.<\/a><\/p>

Shityakov S, Bencurova E, F\u00f6rster C, Dandekar T. 2020. Modeling of shotgun sequencing of\u00a0DNA plasmids using experimental and theoretical approaches<\/b>. BMC Bioinformatics 21(1):132.<\/a><\/p>

Shityakov S, Fischer A, Su KP, Hussein AA, Dandekar T, Broscheit J.\u00a0Novel approach for characterizing propofol binding affinities to 2 serum albumins from different species.\u00a0<\/strong>ACS Omega Article ASAP.<\/a>
doi: 10.1021\/acsomega.0c01295<\/a><\/p>

Stelzner K, Winkler AC, Liang C, Boyny A, Ade CP, Dandekar T, Fraunholz MJ, Rudel T.\u00a02020. Intracellular Staphylococcus aureus Perturbs the Host Cell Ca++ Homeostasis To\u00a0Promote Cell Death<\/b>. mBio 11(6):e02250-20.<\/a><\/p>

Stoll G, Pham M. Beyond recanalization – a call for action in acute stroke<\/strong>. Nat Rev Neurol. 2020 Nov;16(11):591-592.
doi: 10.1038\/s41582-020-00417-0. PMID: 32968233.<\/a><\/p>

Volz J, Kusch C, Beck S, Popp M, V\u00f6gtle T, Meub M, Scheller I, Heil HS, Preu J, Schuhmann MK, Hemmen K, Premsler T, Sickmann A, Heinze KG, Stegner D, Stoll G, Braun A, Sauer M, Nieswandt B. BIN2 orchestrates platelet calcium signaling in thrombosis and thrombo-inflammation<\/strong>. J Clin Invest. 2020 Aug 4:136457.
doi: 10.1172\/JCI136457. Epub ahead of print. PMID: 32750041.<\/a><\/p>

Wolff M, Handtke S, Palankar R, Wesche J, Kohler TP, Kohler C, Gruel Y, Hammerschmidt S, Greinacher A. 2020. Activated platelets kill Staphylococcus aureus, but not Streptococcus pneumoniae \u2013 The role of Fc\u03b3RIIa and platelet factor 4\/heparin antibodies<\/b>. J Thromb Haemost. 18(6):1459-1468.
doi: 10.1111\/jth.14814.<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

\n\t\t\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t

2019<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t\t\t

Binsker U, Kohler TP, and Hammerschmidt S. Contribution of Human Thrombospondin-1 to the Pathogenesis of Gram-Positive Bacteria<\/strong>. 2019 Feb 27. J Innate Immun 11:303-315. (Review).
doi: 10.1159\/000496033<\/a><\/p>

Breitenbach T, Liang C, Beyersdorf N, Dandekar T. Analyzing pharmacological intervention points: A method to calculate external stimuli to switch between steady states in regulatory networks<\/strong>. PLoS Comput Biol. 2019;15(7):e1007075. Published 2019 Jul 16.<\/a>
doi:10.1371\/journal.pcbi.1007075<\/a><\/p>

Breitenbach T, Lorenz K, Dandekar T. How to Steer and Control ERK and the ERK Signaling Cascade Exemplified by Looking at Cardiac Insufficiency<\/strong>. Int J Mol Sci. 2019;20(9):2179. Published 2019 May 2. <\/a>
doi:10.3390\/ijms20092179<\/a><\/p>

Cebo M, Schlotterbeck J, Gawaz M, Chatterjee M, L\u00e4mmerhofer M. Simultaneous targeted and untargeted UHPLC-ESI-MS\/MS method with data-independent acquisition for quantification and profiling of (oxidized) fatty acids released upon platelet activation by thrombin<\/strong>. Anal Chim Acta. 2020;1094:57-69. <\/a>
doi:10.1016\/j.aca.2019.10.005<\/a><\/p>

Dubrovin EV, Barinov NA, Sch\u00e4ffer TE, Klinov DV. In Situ Single-Molecule AFM Investigation of Surface-Induced Fibrinogen Unfolding on Graphite. Langmuir.<\/strong> 2019;35(30):9732-9739.
doi:10.1021\/acs.langmuir.9b01178<\/a><\/p>

Eekels JJM, Althaus K, Bakchoul T, et al. An international external quality assessment for laboratory diagnosis of heparin-induced thrombocytopenia<\/strong>. J Thromb Haemost. 2019;17(3):525-531. <\/a>
doi:10.1111\/jth.14383<\/a><\/p>

Geue S, Aurbach K, Manke MC, et al. Pivotal role of PDK1 in megakaryocyte cytoskeletal dynamics and polarization during platelet biogenesis<\/strong>. Blood. 2019;134(21):1847-1858. <\/a>
doi:10.1182\/blood.2019000185<\/a><\/p>

Gorelashvili MG, Angay O, Hemmen K, Klaus V, Stegner D, Heinze KG. Megakaryocyte volume modulates bone marrow niche properties and cell migration dynamics<\/strong>. Haematologica. 2019 Jun 27. pii: haematol.2018.202010.\u00a0<\/a>
doi: 10.3324\/haematol.2018.202010. [Epub ahead of print] PubMed PMID: 31248970.<\/a><\/p>

Greinacher A, Eekels JJM. Diagnosis of hereditary platelet disorders in the era of next-generation sequencing: „primum non nocere“<\/strong>. J Thromb Haemost. 2019;17(3):551-554.<\/a>
doi:10.1111\/jth.14377<\/a><\/p>

Greinacher A, Eekels JJM. Simplifying the diagnosis of inherited platelet disorders? The new tools do not make it any easier<\/strong>. Blood. 2019;133(23):2478-2483. <\/a>
doi:10.1182\/blood-2019-01-852350<\/a><\/p>

Handtke S, Steil L, Palankar R, et al. Role of Platelet Size Revisited-Function and Protein Composition of Large and Small Platelets<\/strong>. Thromb Haemost. 2019;119(3):407-420.<\/a>
doi:10.1055\/s-0039-1677875<\/a><\/p>

Heinzmann D, Klingel K, M\u00fcller K, Kumbrink J, Kirchner T, Schreieck J, Gawaz M, Seizer P. Mitochondrial Dynamics in Tachycardiomyopathy<\/strong>. Cell Physiol Biochem. 2019;52(3):435-438. <\/a>
<\/a>doi: 10.33594\/000000031. Epub 2019 Mar 15. PubMed PMID: 30873819.<\/a><\/p>

K\u00f6rner A, Schlegel M, Kaussen T, et al. Sympathetic nervous system controls resolution of inflammation via regulation of repulsive guidance molecule<\/strong> A. Nat Commun. 2019;10(1):633. Published 2019 Feb 7. <\/a>
doi:10.1038\/s41467-019-08328-5<\/a><\/p>

Kollikowski AM, Amaya F, Stoll G, M\u00fcllges W, Schuhmann MK, Pham M. Impact of landmark endovascular stroke trials on logistical performance measures: a before-and-after evaluation of real-world data from a regional stroke system of care<\/strong>. J Neurointerv Surg. 2019;11(6):563-568. <\/a>
doi:10.1136\/neurintsurg-2018-014286<\/a><\/p>

Kiran Gotru S, van Geffen JP, Nagy M, Mammadova-Bach E, Eilenberger J, Volz J, Manukjan G, Schulze H, Wagner L, Eber S, Schambeck C, Deppermann C, Brouns S, Nurden P, Greinacher A, Sachs U, Nieswandt B, Hermanns HM, Heemskerk JWM, Braun A. Defective Zn(2+) homeostasis in mouse and human platelets with \u03b1- and \u03b4-storage pool diseases<\/strong>. Sci Rep. 2019 Jun 6;9(1):8333.<\/a>
doi: 10.1038\/s41598-019-44751-w. PubMed PMID: 31171812<\/a><\/p>

Krauel K, Preu\u00dfe P, Warkentin TE, et al. Fibronectin modulates formation of PF4\/heparin complexes and is a potential factor for reducing risk of developing HIT<\/strong>. Blood. 2019;133(9):978-989. <\/a>
doi:10.1182\/blood-2018-05-850370<\/a><\/p>

Nguyen TH, Wesche J, Raschke R, Strobel U, Bui VC, Delcea M, Greinacher A. Reactivity of platelet-activating and nonplatelet-activating anti-PF4\/heparin antibodies in enzyme immunosorbent assays under different conditions<\/strong>. J Thromb Haemost. 2019 Jul;17(7):1113-1119. <\/a>
doi: 10.1111\/jth.14455. Epub 2019 May 17. PubMed PMID: 31009154.<\/a><\/p>

Sauter RJ, Sauter M, Obrich M, et al. Anaphylatoxin Receptor C3aR Contributes to Platelet Function, Thrombus Formation and In Vivo Haemostasis<\/strong>. Thromb Haemost. 2019;119(1):179-182. <\/a>
doi:10.1055\/s-0038-1676349<\/a><\/p>

Schuhmann MK, Kraft P, Bieber M, Kollikowski AM, Schulze H, Nieswandt B, Pham M, Stegner D, Stoll G. Targeting Platelet GPVI Plus rt-PA Administration but Not \u03b12\u03b21-Mediated Collagen Binding Protects against Ischemic Brain Damage in Mice<\/strong>. Int J Mol Sci. 2019 Apr 24;20(8). pii: E2019.
doi: 10.3390\/ijms20082019. PubMed PMID: 31022936; PubMed Central<\/a><\/p>

Schuhmann MK, Stoll G, Bohr A, Volkmann J, Fluri F. Electrical Stimulation of the Mesencephalic Locomotor Region Attenuates Neuronal Loss and Cytokine Expression in the Perifocal Region of Photothrombotic Stroke in Rats<\/strong>. Int J Mol Sci. 2019 May 11;20(9). pii: E2341.\u00a0<\/a>
doi: 10.3390\/ijms20092341. PubMed PMID: 31083528<\/a><\/p>

Schuhmann MK, Stoll G, Papp L, Bohr A, Volkmann J, Fluri F. Electrical Stimulation of the Mesencephalic Locomotor Region Has No Impact on Blood-Brain Barrier Alterations after Cerebral Photothrombosis in Rats<\/strong>. Int J Mol Sci. 2019 Aug 19;20(16). pii: E4036.
doi: 10.3390\/ijms20164036. PubMed PMID: 31430854<\/a><\/p>

Schurr Y, Sperr A, Volz J, et al. Platelet lamellipodium formation is not required for thrombus formation and stability<\/strong>. Blood. 2019;134(25):2318-2329.
doi:10.1182\/blood.2019002105\u00a0<\/a><\/p>

Schurr Y, Spindler M, Kurz H, Bender M. The cytoskeletal crosslinking protein MACF1 is dispensable for thrombus formation and hemostasis<\/strong>. Sci Rep. 2019;9(1):7726. Published 2019 May 22. <\/a>
doi:10.1038\/s41598-019-44183-6<\/a><\/p>

Semeniak D, Faber K, \u00d6ftering P, Manukjan G, Schulze H. Impact of Itga2-Gp6-double collagen receptor deficient mice for bone marrow megakaryocytes and platelets<\/strong>. PLoS One. 2019;14(8):e0216839. Published 2019 Aug 9. <\/a>
doi:10.1371\/journal.pone.0216839<\/a><\/p>

Shvedova M, Litvak MM, Roberts JD Jr, Fukumura D, Suzuki T, \u015eencan \u0130, Li G, Reventun P, Buys ES, Kim HH, Sakad\u017ei\u0107 S, Ayata C, Huang PL, Feil R, Atochin DN. cGMP-dependent protein kinase I in vascular smooth muscle cells improves ischemic stroke outcome in mice<\/strong>. J Cereb Blood Flow Metab. 2019 Aug 18:271678X19870583. <\/a>
doi: 10.1177\/0271678X19870583. [Epub ahead of print] PubMed PMID: 31423931.<\/a><\/p>

Simeonov S , Sch\u00e4ffer TE . High-speed scanning ion conductance microscopy for sub-second topography imaging of live cells. Nanoscale.<\/strong> 2019;11(17):8579-8587.<\/a>
doi:10.1039\/c8nr10162k<\/a><\/p>

Stegner D, Hofmann S, Schuhmann MK, Kraft P, Herrmann AM, Popp S, H\u00f6hn M, Popp M, Klaus V, Post A, Kleinschnitz C, Braun A, Meuth SG, Lesch KP, Stoll G, Kraft R, Nieswandt B. Loss of Orai2-Mediated Capacitative Ca(2+) Entry Is\u00a0Neuroprotective in Acute Ischemic Stroke.<\/strong> Stroke. 2019 Nov;50(11):3238-3245.
doi: 10.1161\/STROKEAHA.119.025357. Epub 2019 Sep 25. PubMed PMID: 31551038.<\/a><\/p>

Stoll G, Nieswandt B. Thrombo-inflammation in acute ischaemic stroke – implications for treatment<\/strong>. Nat Rev Neurol. 2019 Jul 1.
doi: 10.1038\/s41582-019-0221-1. [Epub ahead of print] Review. PubMed PMID: 31263257.<\/a><\/p>

Volz J, Mammadova-Bach E, Gil-Pulido J, et al. Inhibition of platelet GPVI induces intratumor hemorrhage and increases efficacy of chemotherapy in mice<\/strong>. Blood. 2019;133(25):2696-2706. <\/a>
doi:10.1182\/blood.2018877043<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

\n\t\t\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t

2018<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t\t\t

Droppa M, Borst O, Katzenberger T, Krause R, Bramlage K, Bramlage P, Lausberg HF, Schlensak C, Grasshoff C, Gawaz M, Geisler T. Clinical and economical impact of the presence of an extended heart team throughout the balloon-expandable transcatheter aortic valve implantation procedure. <\/b>Clin Res Cardiol. 2018 Aug 24.doi: 10.1007\/s00392-018-1359-3. [Epub ahead of print] PubMed PMID: 30167808<\/a><\/p>\n

Peng B, Geue S, Coman C, M\u00fcnzer P, Kopczynski D, Has C, Hoffmann N, Manke MC, Lang F, Sickmann A, Gawaz M, Borst O, Ahrends R. Identification of key lipids critical for platelet activation by comprehensive analysis of the platelet lipidome<\/b>. Blood. 2018 Aug 2;132(5):e1-e12. doi: 10.1182\/blood-2017-12-822890. Epub 2018 May 21. PubMed PMID: 29784642; PubMed Central PMCID: PMC6137561.<\/a><\/p>\n

Sauter RJ, Sauter M, Reis ES, Emschermann FN, Nording H, Ebenh\u00f6ch S, Kraft P, M\u00fcnzer P, Mauler M, Rheinlaender J, Madlung J, Edlich F, Sch\u00e4ffer TE, Meuth SG, D\u00fcerschmied D, Geisler T, Borst O, Gawaz M, Kleinschnitz C, Lambris JD, Langer HF. A Functional Relevance of the Anaphylatoxin Receptor C3aR for Platelet Function and Arterial Thrombus Formation Marks an Intersection Point Between Innate Immunity and Thrombosis.<\/b> Circulation. 2018 May 25. pii:CIRCULATIONAHA.118.034600. doi: 10.1161\/CIRCULATIONAHA.118.034600. [Epub ahead of print] PubMed PMID: 29802205<\/a><\/p>\n

Spindler M, van Eeuwijk JMM, Schurr Y, Nurden P, Nieswandt B, Stegner D, Reinhold A, Bender M. ADAP deficiency impairs megakaryocyte polarization with ectopic proplatelet release and causes microthrombocytopenia.<\/b> Blood. 2018 Aug 9;132(6):635-646. doi: 10.1182\/blood-2018-01-829259. Epub 2018 Jun 27. PubMed PMID: 29950291<\/a><\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

2023 Beck S, \u00d6ftering P, Li R, Hemmen K, Nagy M, Wang Y, Zarpellon A, Schuhmann MK, Stoll G, Ruggeri ZM, Heinze KG, Heemskerk JWM, Ruf W*, Stegner D*, Nieswandt […]<\/p>\n","protected":false},"author":1,"featured_media":112,"parent":2429,"menu_order":4,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-1896","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"\nPublikationen - The W\u00fcrzburg Platelet Group<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.platelets.eu\/tr240\/publications\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Publikationen - The W\u00fcrzburg Platelet Group\" \/>\n<meta property=\"og:description\" content=\"2023 Beck S, \u00d6ftering P, Li R, Hemmen K, Nagy M, Wang Y, Zarpellon A, Schuhmann MK, Stoll G, Ruggeri ZM, Heinze KG, Heemskerk JWM, Ruf W*, Stegner D*, Nieswandt […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.platelets.eu\/tr240\/publications\/\" \/>\n<meta property=\"og:site_name\" content=\"The W\u00fcrzburg Platelet Group\" \/>\n<meta property=\"article:modified_time\" content=\"2023-12-06T15:06:18+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.platelets.eu\/wp-content\/uploads\/2018\/11\/180514_ex_bio_I_DSC_9011.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"2048\" \/>\n\t<meta property=\"og:image:height\" content=\"1363\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Gesch\u00e4tzte Lesezeit\" \/>\n\t<meta name=\"twitter:data1\" content=\"38\u00a0Minuten\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.platelets.eu\\\/tr240\\\/publications\\\/\",\"url\":\"https:\\\/\\\/www.platelets.eu\\\/tr240\\\/publications\\\/\",\"name\":\"Publikationen - The W\u00fcrzburg Platelet Group\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.platelets.eu\\\/de\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.platelets.eu\\\/tr240\\\/publications\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.platelets.eu\\\/tr240\\\/publications\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.platelets.eu\\\/wp-content\\\/uploads\\\/2018\\\/11\\\/180514_ex_bio_I_DSC_9011.jpg\",\"datePublished\":\"2018-12-11T13:23:52+00:00\",\"dateModified\":\"2023-12-06T15:06:18+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.platelets.eu\\\/tr240\\\/publications\\\/#breadcrumb\"},\"inLanguage\":\"de\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.platelets.eu\\\/tr240\\\/publications\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"de\",\"@id\":\"https:\\\/\\\/www.platelets.eu\\\/tr240\\\/publications\\\/#primaryimage\",\"url\":\"https:\\\/\\\/www.platelets.eu\\\/wp-content\\\/uploads\\\/2018\\\/11\\\/180514_ex_bio_I_DSC_9011.jpg\",\"contentUrl\":\"https:\\\/\\\/www.platelets.eu\\\/wp-content\\\/uploads\\\/2018\\\/11\\\/180514_ex_bio_I_DSC_9011.jpg\",\"width\":2048,\"height\":1363},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.platelets.eu\\\/tr240\\\/publications\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.platelets.eu\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"TR 240 – Platelets\",\"item\":\"https:\\\/\\\/www.platelets.eu\\\/tr240\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Publikationen\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.platelets.eu\\\/de\\\/#website\",\"url\":\"https:\\\/\\\/www.platelets.eu\\\/de\\\/\",\"name\":\"The W\u00fcrzburg Platelet Group\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.platelets.eu\\\/de\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.platelets.eu\\\/de\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"de\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www.platelets.eu\\\/de\\\/#organization\",\"name\":\"The W\u00fcrzburg Platelet Group\",\"url\":\"https:\\\/\\\/www.platelets.eu\\\/de\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"de\",\"@id\":\"https:\\\/\\\/www.platelets.eu\\\/de\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/www.platelets.eu\\\/wp-content\\\/uploads\\\/2018\\\/11\\\/uni-wuerzburg-logo.svg\",\"contentUrl\":\"https:\\\/\\\/www.platelets.eu\\\/wp-content\\\/uploads\\\/2018\\\/11\\\/uni-wuerzburg-logo.svg\",\"caption\":\"The W\u00fcrzburg Platelet Group\"},\"image\":{\"@id\":\"https:\\\/\\\/www.platelets.eu\\\/de\\\/#\\\/schema\\\/logo\\\/image\\\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Publikationen - The W\u00fcrzburg Platelet Group","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.platelets.eu\/tr240\/publications\/","og_locale":"de_DE","og_type":"article","og_title":"Publikationen - The W\u00fcrzburg Platelet Group","og_description":"2023 Beck S, \u00d6ftering P, Li R, Hemmen K, Nagy M, Wang Y, Zarpellon A, Schuhmann MK, Stoll G, Ruggeri ZM, Heinze KG, Heemskerk JWM, Ruf W*, Stegner D*, Nieswandt […]","og_url":"https:\/\/www.platelets.eu\/tr240\/publications\/","og_site_name":"The W\u00fcrzburg Platelet Group","article_modified_time":"2023-12-06T15:06:18+00:00","og_image":[{"width":2048,"height":1363,"url":"https:\/\/www.platelets.eu\/wp-content\/uploads\/2018\/11\/180514_ex_bio_I_DSC_9011.jpg","type":"image\/jpeg"}],"twitter_card":"summary_large_image","twitter_misc":{"Gesch\u00e4tzte Lesezeit":"38\u00a0Minuten"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.platelets.eu\/tr240\/publications\/","url":"https:\/\/www.platelets.eu\/tr240\/publications\/","name":"Publikationen - The W\u00fcrzburg Platelet Group","isPartOf":{"@id":"https:\/\/www.platelets.eu\/de\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.platelets.eu\/tr240\/publications\/#primaryimage"},"image":{"@id":"https:\/\/www.platelets.eu\/tr240\/publications\/#primaryimage"},"thumbnailUrl":"https:\/\/www.platelets.eu\/wp-content\/uploads\/2018\/11\/180514_ex_bio_I_DSC_9011.jpg","datePublished":"2018-12-11T13:23:52+00:00","dateModified":"2023-12-06T15:06:18+00:00","breadcrumb":{"@id":"https:\/\/www.platelets.eu\/tr240\/publications\/#breadcrumb"},"inLanguage":"de","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.platelets.eu\/tr240\/publications\/"]}]},{"@type":"ImageObject","inLanguage":"de","@id":"https:\/\/www.platelets.eu\/tr240\/publications\/#primaryimage","url":"https:\/\/www.platelets.eu\/wp-content\/uploads\/2018\/11\/180514_ex_bio_I_DSC_9011.jpg","contentUrl":"https:\/\/www.platelets.eu\/wp-content\/uploads\/2018\/11\/180514_ex_bio_I_DSC_9011.jpg","width":2048,"height":1363},{"@type":"BreadcrumbList","@id":"https:\/\/www.platelets.eu\/tr240\/publications\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.platelets.eu\/"},{"@type":"ListItem","position":2,"name":"TR 240 – Platelets","item":"https:\/\/www.platelets.eu\/tr240\/"},{"@type":"ListItem","position":3,"name":"Publikationen"}]},{"@type":"WebSite","@id":"https:\/\/www.platelets.eu\/de\/#website","url":"https:\/\/www.platelets.eu\/de\/","name":"The W\u00fcrzburg Platelet Group","description":"","publisher":{"@id":"https:\/\/www.platelets.eu\/de\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.platelets.eu\/de\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"de"},{"@type":"Organization","@id":"https:\/\/www.platelets.eu\/de\/#organization","name":"The W\u00fcrzburg Platelet Group","url":"https:\/\/www.platelets.eu\/de\/","logo":{"@type":"ImageObject","inLanguage":"de","@id":"https:\/\/www.platelets.eu\/de\/#\/schema\/logo\/image\/","url":"https:\/\/www.platelets.eu\/wp-content\/uploads\/2018\/11\/uni-wuerzburg-logo.svg","contentUrl":"https:\/\/www.platelets.eu\/wp-content\/uploads\/2018\/11\/uni-wuerzburg-logo.svg","caption":"The W\u00fcrzburg Platelet Group"},"image":{"@id":"https:\/\/www.platelets.eu\/de\/#\/schema\/logo\/image\/"}}]}},"_links":{"self":[{"href":"https:\/\/www.platelets.eu\/de\/wp-json\/wp\/v2\/pages\/1896","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.platelets.eu\/de\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.platelets.eu\/de\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.platelets.eu\/de\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.platelets.eu\/de\/wp-json\/wp\/v2\/comments?post=1896"}],"version-history":[{"count":10,"href":"https:\/\/www.platelets.eu\/de\/wp-json\/wp\/v2\/pages\/1896\/revisions"}],"predecessor-version":[{"id":4454,"href":"https:\/\/www.platelets.eu\/de\/wp-json\/wp\/v2\/pages\/1896\/revisions\/4454"}],"up":[{"embeddable":true,"href":"https:\/\/www.platelets.eu\/de\/wp-json\/wp\/v2\/pages\/2429"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.platelets.eu\/de\/wp-json\/wp\/v2\/media\/112"}],"wp:attachment":[{"href":"https:\/\/www.platelets.eu\/de\/wp-json\/wp\/v2\/media?parent=1896"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}