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The Chair of Experimental Biomedicine I,
University Hospital Würzburg and Rudolf-Virchow-Center/University Würzburg, Germany, invites applications for

1 PhD student position (f/m/d)

to investigate the crosstalk between hematopoiesis and cardiovascular diseases embedded in the DFG-funded Collaborative Research Center CRC 1525 “Cardio-Immune Interfaces”.

Together, heart failure and ischemic heart diseases are the leading cause of death worldwide and the most common cause of hospitalization in Germany. Compelling recent evidence from clinical and basic research studies has revealed that inflammatory interfaces play crucial roles in the initiation and progression of heart diseases. The causal relationship between systemic leukocytosis and heart failure progression is well documented; however, the underlying mechanisms are still unknown.

Activities and responsibilities

We are seeking a highly motivated PhD student to work on a project that combines advanced imaging techniques with mouse models of cardiovascular disease and/or systemic inflammation. Besides intra-vital two-photon microscopy and light-sheet fluorescence microscopy, genetically modified mice, and functional cellular assays as well as biochemical and molecular biology approaches will be part of the project. Aim is to provide new insights into the crosstalk between hematopoiesis and cardiovascular diseases on several levels.

Qualification profile

Suitable candidates should hold a Master’s degree or equivalent in a life sciences subject with a strong interest in molecular and (vascular) cell biology/immunology, mouse models and different imaging techniques. Excellent lab skills and good knowledge of the English language are a prerequisite. Previous experience with in vivo work and/or advanced imaging techniques is highly advantageous but not mandatory.

Benefits

We offer an international and excellent scientific environment that is embedded in the framework of a German wide research consortium CRC 1525 ‘Cardio-Immune Interfaces’. Its infrastructure is unique in the platelet research field and offers the opportunity to collaborate with national and international basic and translational research groups. The department involves several research labs consisting of post-doctoral scientists, PhD students, master students and research assistants and comes along with a pleasant working atmosphere.

As a PhD student you will have the opportunity to become part of the international ‘Graduate School of Life Sciences’ (GSLS). The university furthermore offers comprehensive services concerning administrative and practical matters, e.g. the Welcome Centre (moving to Würzburg) and the International Office.

The salary for this temporary position is commensurate with training and experience according to Collective Agreement for the Public Service of German Federal States TV-L (E13 (65%). We particularly encourage female scientists to apply. Disabled applicants will be preferentially considered in case of equivalent qualification.

Send applications to

The position will start on March 1st, 2022 or later. Applications should be sent as a single pdf-document including application letter, curriculum vitae, certificates including contact details of two references by e-mail until January 31st, 2022 to Prof. Dr. David Stegner (career@platelets.eu).

For further questions, please do not hesitate to contact Prof. Dr. David Stegner (stegner@virchow.uni-wuerzburg.de).